Detalhe da pesquisa
1.
Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide.
Biochemistry
; 59(4): 541-551, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31841311
2.
GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein.
Antimicrob Agents Chemother
; 59(11): 7109-12, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324264
3.
Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus.
PLoS One
; 17(12): e0271145, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36477212
4.
Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.
Biochemistry
; 50(10): 1567-81, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21222490
5.
Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition.
Biochim Biophys Acta Gen Subj
; 1864(4): 129531, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953125
6.
The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.
J Mol Biol
; 431(7): 1440-1459, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753871
7.
Phosphoethanolamine N-methyltransferase (PMT-1) catalyses the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans.
Biochem J
; 404(3): 439-48, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17313371
8.
Direct binding of ledipasvir to HCV NS5A: mechanism of resistance to an HCV antiviral agent.
PLoS One
; 10(4): e0122844, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25856426
9.
Large-scale functional purification of recombinant HIV-1 capsid.
PLoS One
; 8(3): e58035, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23472130
10.
Three routes to suppression of the neurodegenerative phenotypes caused by kinesin heavy chain mutations.
Genetics
; 192(1): 173-83, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22714410
11.
Lipid-sensing high-throughput ApoA-I assays.
J Biomol Screen
; 17(8): 1050-61, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22811478
12.
The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function.
PLoS One
; 7(6): e39163, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22720059
13.
Visualizing ATP-dependent RNA translocation by the NS3 helicase from HCV.
J Mol Biol
; 405(5): 1139-53, 2011 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145896
14.
Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design.
J Med Chem
; 53(10): 4295-9, 2010 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20438081
15.
The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties.
J Mol Biol
; 400(3): 354-78, 2010 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20451531
16.
Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.
J Mol Biol
; 397(4): 967-78, 2010 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20156454
17.
RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.
J Med Chem
; 52(19): 5781-4, 2009 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19791799
18.
Defining the role of phosphomethylethanolamine N-methyltransferase from Caenorhabditis elegans in phosphocholine biosynthesis by biochemical and kinetic analysis.
Biochemistry
; 45(19): 6056-65, 2006 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16681378
19.
Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain.
Proc Natl Acad Sci U S A
; 102(29): 10076-81, 2005 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16009938
20.
Motor domain mutation traps kinesin as a microtubule rigor complex.
Biochemistry
; 42(9): 2595-606, 2003 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-12614154